The medical check is mandatory for all third-country national permit applicants — but EU family members and long-term EU residents are exempt.
Overview
Luxembourg's mandatory medical check-up (contrôle médical obligatoire) is required of all third-country nationals applying for a residence permit for stays exceeding 3 months. It is not a visa-stage requirement but a post-arrival one: it must be completed after receiving the temporary authorisation to stay and before the residence permit can be issued. The check has two components: a full clinical examination by a doctor established in Luxembourg and authorised as a GP, internist or paediatrician; and a tuberculosis (TB) screening performed at a medical analysis laboratory in Luxembourg or at the Ligue médico-sociale (LMS) for children aged 2 months to 2 years. Following the GP examination, the doctor issues a temporary medical certificate on the Ministry of Health and Social Security's official form and must send it in a sealed envelope to the Health Inspection at the Health Directorate (Direction de la Santé) within one month. The Health Directorate then issues the final medical certificate and sends it to the General Department of Immigration — without which the permit application cannot be processed. Costs are borne by the applicant; no fixed national tariff exists. Exemptions apply to EU-citizen family members and long-term EU residents. Verified against guichet.public.lu as of June 2026.
Medical Check Components and Who Must Undergo Them
| Component | Who performs it | Who must attend | Exemptions |
|---|---|---|---|
| Clinical examination: general exam, blood test (STI check per symptoms, excl. HIV/AIDS), vaccination check, glucose test (if at risk), urine test | Luxembourg GP, internal medicine specialist, or paediatrician — authorised and established in Luxembourg | All third-country national residence permit applicants (stays >3 months) | EU-citizen family members; long-term EU residents and their family members |
| TB screening — IGRA or tuberculin test | Medical analysis laboratory (any, for ages 2+) or Ligue médico-sociale (LMS) | All TCN permit applicants aged 2 months and over | Same as above |
| TB screening — tuberculin test only | Ligue médico-sociale (LMS) — mandatory venue for this age group | Children aged 2 months to 2 years | N/A — LMS is the required venue for this group |
| Health Directorate final certificate | Health Inspection, Direction de la Santé | Issued after GP certificate + TB screening confirmation received | No action required by applicant — Health Directorate sends directly to General Department of Immigration |
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See Paid Plans →Frequently Asked Questions
Is HIV/AIDS tested as part of the Luxembourg immigration medical check?
No. The blood test component of the Luxembourg mandatory medical examination explicitly excludes HIV/AIDS testing. The blood test checks for sexually transmitted diseases only 'depending on the clinical symptomatology' — meaning it is not a routine screen of all applicants but is conducted at the GP's clinical discretion. Luxembourg does not screen immigration applicants for HIV/AIDS status as a condition of residence. This is consistent with EU human rights standards and the Directive 2003/9/EC framework.
Which Luxembourg doctor can do the immigration medical examination?
Any doctor established in Luxembourg and authorised to practise as a general practitioner, specialist in internal medicine, or paediatrician. There is no 'panel physician' approved list — unlike some countries (e.g. Australia or Canada) that designate specific immigration medical examiners. You can go to any authorised GP in Luxembourg. The GP must use the official medical certificate form provided by the Ministry of Health and Social Security (Ministère de la Santé et de la Sécurité sociale) and send it directly to the Health Directorate within one month of the examination.
Where do I go for TB screening, and what happens if the result is positive?
For anyone aged 2 years and over, TB screening can be done at any medical analysis laboratory in Luxembourg. Children aged 2 months to 2 years must attend the Ligue médico-sociale (LMS) specifically. The screening checks for active, contagious TB or TB likely to develop. If the screening is positive, treatment will be required and the Health Directorate will assess the situation before issuing its final certificate. Active, contagious TB is a listed ground for permit refusal, but treated or latent TB is assessed differently — seek medical advice if you have a history of TB before applying.
Are family members of an EU citizen exempt from the Luxembourg medical check?
Yes. Third-country nationals who are family members of an EU citizen (or national of Iceland, Liechtenstein, Norway or Switzerland) residing in Luxembourg are exempt from the mandatory medical check-up. Similarly, long-term residents from another EU member state and their family members are exempt. These groups still need a residence permit (family member of EU citizen permit, free of the €80 standard fee for EU-citizen family members), but they do not need to undergo the GP examination or TB screening as part of that process.
How long does the whole medical check process take from booking to permit clearance?
Allow at minimum 4–6 weeks from your first GP appointment to the Health Directorate issuing its final certificate. The GP has up to 1 month to send the certificate; the laboratory or LMS must also confirm the TB screening. The Health Directorate then processes both. If you book the GP in week 1 after arrival and the GP sends the certificate promptly, the clearance certificate can reach the General Department of Immigration within 6–8 weeks of arrival. If you delay the medical to week 6 or 8, the permit will not be issued until month 3 or 4 at earliest — potentially creating an authorisation-to-stay gap.
Does Luxembourg require any vaccination certificates for immigration?
Luxembourg does not require specific immigration vaccination certificates as a pre-condition for applying. However, the GP who conducts the mandatory medical examination checks that vaccinations are up to date against the Luxembourg national vaccination schedule. If vaccinations are found to be incomplete, the GP may recommend catch-up vaccinations — but this is a clinical recommendation during the examination, not a separate pre-arrival requirement. There are no mandatory yellow fever, polio, or other specific vaccination certificates required in the immigration application documents.

